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24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) is an oxysterol compound that is an activator of the n-methyl-d-aspartate receptor (NMDA) and the transcription factor LXR, which has been used in the study of cardiogenesis and pancreatic cancer.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $129 | Backorder |
Description | 24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) is an oxysterol compound that is an activator of the n-methyl-d-aspartate receptor (NMDA) and the transcription factor LXR, which has been used in the study of cardiogenesis and pancreatic cancer. |
In vitro | During the angiogenic switch in rat insulin promoter 1-T-antigen 2 (RIP1-Tag2) pNET formation, the oxysterol-generating enzyme Cyp46a1 overexpressed 24-Hydroxycholesterol[1]. |
In vivo | In mouse in vivo experiments,24S-HC(24-Hydroxycholesterol) plays a major role in the local recruitment of neutrophils during angiogenesis. Immunofluorescence analysis reveals neutrophils proximal to cells producing 24S-HC(24-Hydroxycholesterol), namely Cyp46a1 cells [1]. |
Alias | Cholest-5-ene-3beta,24-diol |
Molecular Weight | 402.65 |
Formula | C27H46O2 |
Cas No. | 30271-38-6 |
Smiles | [H][C@@]12CC[C@H]([C@H](C)CCC(O)C(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C |
Relative Density. | 1.03 g/cm3 (Predicted) |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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