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Aurachin D

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Catalog No. T80016Cas No. 108354-13-8

Aurachin D, a cytotoxic quinolone targeting Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase, acts as an antibiotic against malaria, Plasmodium spp, T. cruzi and Leishmania donovani, can be used to study visceral leishmaniasis.

Aurachin D

Aurachin D

😃Good
Catalog No. T80016Cas No. 108354-13-8
Aurachin D, a cytotoxic quinolone targeting Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase, acts as an antibiotic against malaria, Plasmodium spp, T. cruzi and Leishmania donovani, can be used to study visceral leishmaniasis.
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Product Introduction

Bioactivity
Description
Aurachin D, a cytotoxic quinolone targeting Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase, acts as an antibiotic against malaria, Plasmodium spp, T. cruzi and Leishmania donovani, can be used to study visceral leishmaniasis.
Chemical Properties
Molecular Weight363.54
FormulaC25H33NO
Cas No.108354-13-8
SmilesO=C1C=2C(NC(C)=C1C/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)=CC=CC2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 40 mg/mL (110.03 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7507 mL13.7536 mL27.5073 mL137.5364 mL
5 mM0.5501 mL2.7507 mL5.5015 mL27.5073 mL
10 mM0.2751 mL1.3754 mL2.7507 mL13.7536 mL
20 mM0.1375 mL0.6877 mL1.3754 mL6.8768 mL
50 mM0.0550 mL0.2751 mL0.5501 mL2.7507 mL
100 mM0.0275 mL0.1375 mL0.2751 mL1.3754 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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