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Aurachin D

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Catalog No. T80016Cas No. 108354-13-8

Aurachin D, a cytotoxic quinolone targeting Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase, acts as an antibiotic against malaria, Plasmodium spp, T. cruzi and Leishmania donovani, can be used to study visceral leishmaniasis.

Aurachin D

Aurachin D

😃Good
Catalog No. T80016Cas No. 108354-13-8
Aurachin D, a cytotoxic quinolone targeting Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase, acts as an antibiotic against malaria, Plasmodium spp, T. cruzi and Leishmania donovani, can be used to study visceral leishmaniasis.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Aurachin D, a cytotoxic quinolone targeting Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase, acts as an antibiotic against malaria, Plasmodium spp, T. cruzi and Leishmania donovani, can be used to study visceral leishmaniasis.
Chemical Properties
Molecular Weight363.54
FormulaC25H33NO
Cas No.108354-13-8
SmilesO=C1C=2C(NC(C)=C1C/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)=CC=CC2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (110.03 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7507 mL13.7536 mL27.5073 mL137.5364 mL
5 mM0.5501 mL2.7507 mL5.5015 mL27.5073 mL
10 mM0.2751 mL1.3754 mL2.7507 mL13.7536 mL
20 mM0.1375 mL0.6877 mL1.3754 mL6.8768 mL
50 mM0.0550 mL0.2751 mL0.5501 mL2.7507 mL
100 mM0.0275 mL0.1375 mL0.2751 mL1.3754 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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