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Anti-IL-17 Antibody (5K260) (Synonyms: interleukin 17A)

Catalog No. TMAY-02209 Copy Product Info
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Anti-IL-17 Antibody (5K260) is a Mouse antibody targeting IL-17. Anti-IL-17 Antibody (5K260) can be used in ELISA(Cap).

Anti-IL-17 Antibody (5K260)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02209
Synonyms interleukin 17A

Anti-IL-17 Antibody (5K260) is a Mouse antibody targeting IL-17. Anti-IL-17 Antibody (5K260) can be used in ELISA(Cap).

Anti-IL-17 Antibody
(5K260)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$937-10 days7-10 days
100 μL$2707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-17 Antibody (5K260) is a Mouse antibody targeting IL-17. Anti-IL-17 Antibody (5K260) can be used in ELISA(Cap).
Synonymsinterleukin 17A
Ig Type
Mouse IgG1
Clone
5K260
Reactivity
Human
Specificity
Human IL-17A
Application
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17A/IL-17A/IL17 (rh IL17A/IL-17A/IL17; TMPY-02886; Q16552; Ile20-Ala155). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
Research BackgroundIL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IL17A/IL-17A/IL17 Protein (TMPY-02886)
Antigen Species
Human
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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