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N-Acetyl-Calicheamicin

Name: N-Acetyl-Calicheamicin
Brand: TargetMol
SKU: T12140
Price: 496 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12140Cas No. 108212-76-6

Alias N-Acetyl-γ-calicheamicin, N-Acetyl-Calicheamicin γ

N-Acetyl-Calicheamicin (N-Acetyl-γ-calicheamicin) is an antibiotic with high anti-tumor activity.

N-Acetyl-Calicheamicin

🥰Excellent

Purity: 99.59%

Catalog No. T12140Alias N-Acetyl-γ-calicheamicin, N-Acetyl-Calicheamicin γCas No. 108212-76-6

N-Acetyl-Calicheamicin (N-Acetyl-γ-calicheamicin) is an antibiotic with high anti-tumor activity.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$496	-	In Stock
5 mg	$1,230	-	In Stock
10 mg	$1,670	-	In Stock
25 mg	$2,480	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.59%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	N-Acetyl-Calicheamicin (N-Acetyl-γ-calicheamicin) is an antibiotic with high anti-tumor activity.
Synonyms	N-Acetyl-γ-calicheamicin, N-Acetyl-Calicheamicin γ

Chemical Properties

Molecular Weight	1410.38
Formula	C₅₇H₇₆IN₃O₂₂S₄
Cas No.	108212-76-6
Smiles	C(\CSSSC)=C/1\C=2[C@@H](O[C@H]3[C@H](O[C@H]4C[C@H](OC)[C@@H](N(C(C)=O)CC)CO4)[C@@H](O)[C@H](NO[C@H]5C[C@H](O)[C@H](SC(=O)C6=C(OC)C(OC)=C(O[C@H]7[C@H](O)[C@H](OC)[C@@H](O)[C@H](C)O7)C(I)=C6C)[C@@H](C)O5)[C@@H](C)O3)C#C/C=C/C#C[C@]1(O)CC(=O)C2NC(OC)=O
Relative Density.	1.56 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 70.52 mg/mL (50 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.7090 mL	3.5451 mL	7.0903 mL	35.4514 mL
5 mM	0.1418 mL	0.7090 mL	1.4181 mL	7.0903 mL
10 mM	0.0709 mL	0.3545 mL	0.7090 mL	3.5451 mL
20 mM	0.0355 mL	0.1773 mL	0.3545 mL	1.7726 mL
50 mM	0.0142 mL	0.0709 mL	0.1418 mL	0.7090 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc