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Carindacillin sodium

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Catalog No. T40295Cas No. 26605-69-6
Alias CP-15464-2, Carbenicillin indanyl sodium

Carindacillin sodium is an orally active prodrug of carbenicillin, a penicillin antibiotic that exerts broad-spectrum antibacterial activity by interfering with cell wall synthesis.

Carindacillin sodium

Carindacillin sodium

Copy Product Info
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Catalog No. T40295Alias CP-15464-2, Carbenicillin indanyl sodiumCas No. 26605-69-6
Carindacillin sodium is an orally active prodrug of carbenicillin, a penicillin antibiotic that exerts broad-spectrum antibacterial activity by interfering with cell wall synthesis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$53-In Stock
5 mg$975 days5 days
10 mg$1875 days5 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:Brown
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Product Introduction

Bioactivity
Description
Carindacillin sodium is an orally active prodrug of carbenicillin, a penicillin antibiotic that exerts broad-spectrum antibacterial activity by interfering with cell wall synthesis.
In vitro
Carindacillin sodium is active against a broad spectrum of bacterial species in vitro, effectively inhibiting the growth of both Gram-positive and Gram-negative strains [1].
In vivo
Oral administration of Carindacillin sodium protects mice against lethal infections from pathogens like E. coli and S. aureus, with PD95 values ranging from 30.4 to 220.4 mg/kg [1].
SynonymsCP-15464-2, Carbenicillin indanyl sodium
Chemical Properties
Molecular Weight516.54
FormulaC26H25N2NaO6S
Cas No.26605-69-6
SmilesO=C(C(C(N[C@H]1[C@@]2(N([C@@H](C([O-])=O)C(S2)(C)C)C1=O)[H])=O)C3=CC=CC=C3)OC4=CC=C5CCCC5=C4.[Na+]
Storage & Solubility Information
Storagekeep away from moisture | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 250 mg/mL (483.99 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9360 mL9.6798 mL19.3596 mL96.7979 mL
5 mM0.3872 mL1.9360 mL3.8719 mL19.3596 mL
10 mM0.1936 mL0.9680 mL1.9360 mL9.6798 mL
20 mM0.0968 mL0.4840 mL0.9680 mL4.8399 mL
50 mM0.0387 mL0.1936 mL0.3872 mL1.9360 mL
100 mM0.0194 mL0.0968 mL0.1936 mL0.9680 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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