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Etzadroxil

Name: Etzadroxil
Brand: TargetMol
SKU: T35851
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T35851Cas No. 2983-38-2

Alias Ethyl 2-Ethylbutyrate

Etzadroxil (Ethyl 2-Ethylbutyrate) is an orally available and volatile esterification with broad-spectrum antimicrobial activity, effective in treating urinary tract infections caused by multi-drug resistant bacteria.

Etzadroxil

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Purity: 98%

Catalog No. T35851Alias Ethyl 2-EthylbutyrateCas No. 2983-38-2

Pack Size	Price	Availability	Quantity
200 mg	$29	In Stock

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Purity:98%

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COA HNMR

Product Introduction

Bioactivity

Description	Etzadroxil (Ethyl 2-Ethylbutyrate) is an orally available and volatile esterification with broad-spectrum antimicrobial activity, effective in treating urinary tract infections caused by multi-drug resistant bacteria.
In vivo	Sulopenem Etzadroxil is an orally available ester prodrug form of sulopenem. After oral administration of sulopenem etzadroxil, the ester bond is cleaved, releasing active Sulopenem[2].
Synonyms	Ethyl 2-Ethylbutyrate

Chemical Properties

Molecular Weight	144.21
Formula	C₈H₁₆O₂
Cas No.	2983-38-2
Smiles	CCOC(=O)C(CC)CC

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (624.09 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.9343 mL	34.6717 mL	69.3433 mL	346.7166 mL
5 mM	1.3869 mL	6.9343 mL	13.8687 mL	69.3433 mL
10 mM	0.6934 mL	3.4672 mL	6.9343 mL	34.6717 mL
20 mM	0.3467 mL	1.7336 mL	3.4672 mL	17.3358 mL
50 mM	0.1387 mL	0.6934 mL	1.3869 mL	6.9343 mL
100 mM	0.0693 mL	0.3467 mL	0.6934 mL	3.4672 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc