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Satralizumab

(Synonyms: SA-237, SA237, RG-6168, RG6168) Copy Product Info
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Synonyms: SA-237, SA237, RG-6168, RG6168

Catalog No. T76712 Copy Product Info
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Satralizumab (SA-237) is a humanized monoclonal antibody targeting interleukin-6 (IL-6), acting in neuromyelitis optica spectrum disorder (NMOSD). It is used in studies of neuromyelitis optica.

Satralizumab

Cas No. 1535963-91-7
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$213In StockIn Stock
5 mg$538In StockIn Stock
10 mg$868-In Stock
25 mg$1,280-In Stock
50 mg$1,730-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:96.99% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Satralizumab (SA-237) is a humanized monoclonal antibody targeting interleukin-6 (IL-6), acting in neuromyelitis optica spectrum disorder (NMOSD). It is used in studies of neuromyelitis optica.
In vivo
Satralizumab (120 mg/ biweekly, injected subcutaneously) prevents the formation and progression of thoracic descending aortic aneurysm (dTAA) in rats. [1]
SynonymsSA-237, SA237, RG-6168, RG6168
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-6 R alpha/CD126
Chemical Properties
Molecular Weight143.42 kDa
Cas No.1535963-91-7
Antibody Information
IsotypeHuman IgG2 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Satralizumab in vivo | Satralizumab molecular weight