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Colominic acid sodium salt

Name: Colominic acid sodium salt
Brand: TargetMol
SKU: T40814
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T40814Cas No. 70431-34-4

Colominic acid sodium salt is an N-acetylneuraminic acid homopolymer produced by Escherichia coli, used to study the process of protein polysialylation and exhibiting antibacterial activity.

Colominic acid sodium salt

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Catalog No. T40814Cas No. 70431-34-4

Colominic acid sodium salt is an N-acetylneuraminic acid homopolymer produced by Escherichia coli, used to study the process of protein polysialylation and exhibiting antibacterial activity.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$30	-	In Stock
5 mg	$48	-	In Stock
10 mg	$77	-	In Stock
25 mg	$156	-	In Stock
50 mg	$239	-	In Stock
100 mg	$363	-	In Stock
200 mg	$538	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Appearance:Solid

Color:White

Resource Download

COA LCMS

Product Introduction

Bioactivity

Description	Colominic acid sodium salt is an N-acetylneuraminic acid homopolymer produced by Escherichia coli, used to study the process of protein polysialylation and exhibiting antibacterial activity.
In vitro	Colominic acid sodium salt (Polysialic acid) specifically targets a narrow range of central nervous system components through N-glycosylation, including cell adhesion molecules like neural cell adhesion molecule (NCAM), synaptic cell adhesion molecule 1 (SynCAM1), and the neuropilin-2 receptor.[1]

Chemical Properties

Molecular Weight	344.23
Formula	C₁₁H₁₇NNa₃O₇
Cas No.	70431-34-4
Smiles	CC(N[C@@H]1[C@H](CC(OC1[C@@H](C[O-])[O-])O[CH]C[O-])O)=O.[Na+].[Na+].[Na+]
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 80 mg/mL (232.4 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.9050 mL	14.5252 mL	29.0503 mL	145.2517 mL
5 mM	0.5810 mL	2.9050 mL	5.8101 mL	29.0503 mL
10 mM	0.2905 mL	1.4525 mL	2.9050 mL	14.5252 mL
20 mM	0.1453 mL	0.7263 mL	1.4525 mL	7.2626 mL
50 mM	0.0581 mL	0.2905 mL	0.5810 mL	2.9050 mL
100 mM	0.0291 mL	0.1453 mL	0.2905 mL	1.4525 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc