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Zeaxanthin

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Catalog No. TMS2180Cas No. 144-68-3
Alias Anchovyxanthin

Zeaxanthin is a dietary carotenoid that accumulates in the retina (particularly the macula) and has antioxidant activity that may improve obesity, prevent age-related macular degeneration, and protect against nonalcoholic steatohepatitis.

Zeaxanthin
Other Forms of Zeaxanthin:
Zeaxanthin (Standard)TMSM-2403144-68-3
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Zeaxanthin

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Purity: 99.44%
Catalog No. TMS2180Alias AnchovyxanthinCas No. 144-68-3
Zeaxanthin is a dietary carotenoid that accumulates in the retina (particularly the macula) and has antioxidant activity that may improve obesity, prevent age-related macular degeneration, and protect against nonalcoholic steatohepatitis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$61In StockIn Stock
5 mg$163In StockIn Stock
10 mg$263In StockIn Stock
25 mg$455In StockIn Stock
50 mg$683In StockIn Stock
100 mg$928-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.44%
Appearance:Solid
Color:Orange
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Zeaxanthin is a dietary carotenoid that accumulates in the retina (particularly the macula) and has antioxidant activity that may improve obesity, prevent age-related macular degeneration, and protect against nonalcoholic steatohepatitis.
In vitro
METHODS: Free fatty acid (FFA)-induced HepG2 cells were used as a cell model of NAFLD to study the role of Zeaxanthin in HepG2 cells.
RESULTS Zeaxanthin exerts antioxidant and anti-inflammatory effects in FFA-induced HepG2 cells, can significantly reduce the production of reactive oxygen species (ROS) and iron overload, and improve mitochondrial dysfunction in FFA-induced HepG2 cells; Zeaxanthin can also down-regulate The expression of p53, regulating downstream targets such as GPX4, SLC7A11, SAT1 and ALOX15, helps reduce cellular lipid peroxidation. [2]
SynonymsAnchovyxanthin
Chemical Properties
Molecular Weight568.87
FormulaC40H56O2
Cas No.144-68-3
SmilesC\C(\C=C\C=C(/C)\C=C\C1=C(C)C[C@@H](O)CC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C
Relative Density.1.008 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Slightly soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

ZeaxanthintissuesmaculalipophiliceyeEndogenousMetaboliteEndogenous MetabolitecholesterolcarotenoidAntioxidant
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