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Anti-IL-4R Antibody (9B64)

😃Good
Catalog No. TMAY-03769
Alias interleukin 4 receptor, IL-4RA, IL4RA, IL4R, CD124

Anti-IL-4R Antibody (9B64) is a Rabbit antibody targeting IL-4R. Anti-IL-4R Antibody (9B64) can be used in ELISA,FCM.

Anti-IL-4R Antibody (9B64)

Anti-IL-4R Antibody (9B64)

😃Good
Catalog No. TMAY-03769Alias interleukin 4 receptor, IL-4RA, IL4RA, IL4R, CD124
Anti-IL-4R Antibody (9B64) is a Rabbit antibody targeting IL-4R. Anti-IL-4R Antibody (9B64) can be used in ELISA,FCM.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-IL-4R Antibody (9B64) is a Rabbit antibody targeting IL-4R. Anti-IL-4R Antibody (9B64) can be used in ELISA,FCM.
Aliasinterleukin 4 receptor, IL-4RA, IL4RA, IL4R, CD124
Ig Type
Monoclonal Rabbit IgG
Clone
9B64
Reactivity
Rat
Verified Activity
Flow cytometric analysis of rat IL4R(CD124) expression on SD rat splenocytes. Cells were stained with purified anti-rat IL4R(CD124), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
ELISA,FCM
Recommended Dose
ELISA: 1:5000-1:10000; FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Rat IL-4R/CD124 (rR IL-4R/CD124; TMPY-02914; Q63257-1; Met1-Arg232).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD124, also known as the interleukin 4 receptor (IL4R), is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to a soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Rat IL-4R/CD124 Protein (TMPY-02914)
Antigen Species
Rat
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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