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Cefacetrile

Name: Cefacetrile
Brand: TargetMol
SKU: T30785
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T30785Cas No. 10206-21-0

Alias Cephacetrile, Celospor, Cefacetrilum, Cefacetrilo, Cefacetril

Cefacetrile (Cephacetrile) is a broad-spectrum cephalosporin antibiotic with antimicrobial activity, used to study Gram-negative infections, acting similarly to cefotifen.

Cefacetrile

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Purity: 98.38%

Catalog No. T30785Alias Cephacetrile, Celospor, Cefacetrilum, Cefacetrilo, CefacetrilCas No. 10206-21-0

Cefacetrile (Cephacetrile) is a broad-spectrum cephalosporin antibiotic with antimicrobial activity, used to study Gram-negative infections, acting similarly to cefotifen.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$37	-	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.38%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Cefacetrile (Cephacetrile) is a broad-spectrum cephalosporin antibiotic with antimicrobial activity, used to study Gram-negative infections, acting similarly to cefotifen.
In vitro	Inhibiting Staphylococcus aureus and Streptococcus pyogenes, cefacetrile is effective at concentrations less than 1 μg/mL[4].
In vivo	Administered subcutaneously at doses of 50, 100, and 500 mg/kg, cefacetrile does not alter fertility, gestation, and post-natal development of term fetuses in rats, and fertility and gestation in rabbits[3].At an intravenous dose of 1 g/kg, cefacetrile produces no nephrotoxicity in rabbits and rats[2].
Synonyms	Cephacetrile, Celospor, Cefacetrilum, Cefacetrilo, Cefacetril

Chemical Properties

Molecular Weight	339.32
Formula	C₁₃H₁₃N₃O₆S
Cas No.	10206-21-0
Smiles	C(O)(=O)C=1N2[C@@]([C@H](NC(CC#N)=O)C2=O)(SCC1COC(C)=O)[H]
Relative Density.	1.59g/cm3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (235.77 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9471 mL	14.7354 mL	29.4707 mL	147.3535 mL
5 mM	0.5894 mL	2.9471 mL	5.8941 mL	29.4707 mL
10 mM	0.2947 mL	1.4735 mL	2.9471 mL	14.7354 mL
20 mM	0.1474 mL	0.7368 mL	1.4735 mL	7.3677 mL
50 mM	0.0589 mL	0.2947 mL	0.5894 mL	2.9471 mL
100 mM	0.0295 mL	0.1474 mL	0.2947 mL	1.4735 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc