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Dacomitinib Intermediate 2

🥰Excellent
Catalog No. T67152Cas No. 179552-74-0
Alias N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine

Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) has anticancer activity and can be used to study lung cancer.

Dacomitinib Intermediate 2

Dacomitinib Intermediate 2

🥰Excellent
Purity: 99.27%
Catalog No. T67152Alias N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amineCas No. 179552-74-0
Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) has anticancer activity and can be used to study lung cancer.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$35In StockIn Stock
25 mg$56In StockIn Stock
50 mg$82In StockIn Stock
100 mg$118In StockIn Stock
200 mg$175-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.27%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) has anticancer activity and can be used to study lung cancer.
SynonymsN-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
Chemical Properties
Molecular Weight348.72
FormulaC15H10ClFN4O3
Cas No.179552-74-0
SmilesCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1[N+]([O-])=O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 16.67 mg/mL (47.79 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8676 mL14.3382 mL28.6763 mL143.3815 mL
5 mM0.5735 mL2.8676 mL5.7353 mL28.6763 mL
10 mM0.2868 mL1.4338 mL2.8676 mL14.3382 mL
20 mM0.1434 mL0.7169 mL1.4338 mL7.1691 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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