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Anti-CD122/IL2RB Antibody (8K761)
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Catalog No. TMAY-01079
Alias P70-75, interleukin 2 receptor, β, interleukin 2 receptor, beta, IL-15RB, IL15RB, CD122
Anti-CD122/IL2RB Antibody (8K761) is a Mouse antibody targeting CD122/IL2RB. Anti-CD122/IL2RB Antibody (8K761) can be used in ELISA.
Anti-CD122/IL2RB Antibody (8K761)
Anti-CD122/IL2RB Antibody (8K761)
😃Good
Catalog No. TMAY-01079Alias P70-75, interleukin 2 receptor, β, interleukin 2 receptor, beta, IL-15RB, IL15RB, CD122
Anti-CD122/IL2RB Antibody (8K761) is a Mouse antibody targeting CD122/IL2RB. Anti-CD122/IL2RB Antibody (8K761) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Chemical Properties
| Description | Anti-CD122/IL2RB Antibody (8K761) is a Mouse antibody targeting CD122/IL2RB. Anti-CD122/IL2RB Antibody (8K761) can be used in ELISA. |
| Alias | P70-75, interleukin 2 receptor, β, interleukin 2 receptor, beta, IL-15RB, IL15RB, CD122 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8K761 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-2R beta/CD122 (rh IL-2R beta/CD122; TMPY-05216; NP_000869.1; Met1-Asp239). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concerning the ability to bind interleukin 2. The low-affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high-affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high-affinity forms of CD122/IL-2RB are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. CD122/IL-2RB expression was restricted to the earliest B220+ cells (CD43+CD24-; prepro B cells; fraction A) that proliferate vigorously to IL-2 in the absence of any stromal cells, but not to IL-15. The high-affinity form of this receptor is expressed on activated T lymphocytes, activated B lymphocytes, and activated macrophages. CD122/IL-2RB plays a role in regulating normal lymphocyte development. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human IL-2R beta/CD122 Protein (TMPY-05216) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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