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3,4-Dihydroxy-2-methoxyxanthone

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Catalog No. TN2876Cas No. 6702-55-2

3,4-Dihydroxy-2-methoxyxanthone shows antibacterial, and hepatoprotective activities, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes and is effective in preventing perturbation of cell glutathione homeostasis in some extent.

3,4-Dihydroxy-2-methoxyxanthone

3,4-Dihydroxy-2-methoxyxanthone

😃Good
Catalog No. TN2876Cas No. 6702-55-2
3,4-Dihydroxy-2-methoxyxanthone shows antibacterial, and hepatoprotective activities, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes and is effective in preventing perturbation of cell glutathione homeostasis in some extent.
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1 mL x 10 mM (in DMSO)InquiryBackorderBackorder
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Bioactivity
Description
3,4-Dihydroxy-2-methoxyxanthone shows antibacterial, and hepatoprotective activities, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes and is effective in preventing perturbation of cell glutathione homeostasis in some extent.
In vitro
The branches of Kielmeyera by n-hexane isolation of 3,4-Dihydroxy-2-methoxyxanthone, showed moderate to low activity against the tested MRSA strains.[1]
Chemical Properties
Molecular Weight258.23
FormulaC14H10O5
Cas No.6702-55-2
SmilesO=C1C=2C=CC=CC2OC3=C(O)C(O)=C(OC)C=C13
Relative Density.1.480 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

fatty acid oxidation (pFOX)BacterialAntifection3,4-Dihydroxy-2-methoxyxanthone3,4Dihydroxy2methoxyxanthone3,4 Dihydroxy 2 methoxyxanthone
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