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Kanamycin A

Name: Kanamycin A
Brand: TargetMol
SKU: T0793L
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0793LCas No. 59-01-8

Alias Kantrex, KanamycinA, Kanamycin

Kanamycin A (KanamycinA) is an aminoglycoside antibiotic with antibacterial and antiviral activity that inhibits bacterial and viral replication.

Kanamycin A

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Purity: 99.59%

Catalog No. T0793LAlias Kantrex, KanamycinA, KanamycinCas No. 59-01-8

Kanamycin A (KanamycinA) is an aminoglycoside antibiotic with antibacterial and antiviral activity that inhibits bacterial and viral replication.

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$40	In Stock	In Stock
500 mg	$61	In Stock	-
1 g	$87	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.59%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Kanamycin A (KanamycinA) is an aminoglycoside antibiotic with antibacterial and antiviral activity that inhibits bacterial and viral replication.
In vitro	Kanamycin A (0.1-100 μg/mL; 2 weeks of treatment) showed good antimicrobial activity against a wide range of mycobacterial strains in vitro with a minimum inhibitory concentration (MIC) of 1-5 μg/mL. [1]
In vivo	Kanamycin A administered intravenously at doses of 2 mg/kg and 4 mg/kg once a day, six times a week for three weeks effectively inhibited the growth of Mycobacterium bovis in the lungs and spleens of mice. [1] Kanamycin A administered intravenously in a single dose (3 hours post-infection) at 1.25 mg/kg and 5 mg/kg significantly reduced the colonization of K. pneumoniae DT-S in the lungs, trachea and blood of mice and this reduction was proportional to the administered dose, while increasing the survival rate of mice. [2]
Synonyms	Kantrex, KanamycinA, Kanamycin

Chemical Properties

Molecular Weight	484.5
Formula	C₁₈H₃₆N₄O₁₁
Cas No.	59-01-8
Smiles	O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](N)C[C@H]1N)[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O
Relative Density.	1.4042 g/cm3 (Estimated)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 60 mg/mL (123.84 mM), Sonication is recommended.

DMSO: Soluble

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.0640 mL	10.3199 mL	20.6398 mL	103.1992 mL
5 mM	0.4128 mL	2.0640 mL	4.1280 mL	20.6398 mL
10 mM	0.2064 mL	1.0320 mL	2.0640 mL	10.3199 mL
20 mM	0.1032 mL	0.5160 mL	1.0320 mL	5.1600 mL
50 mM	0.0413 mL	0.2064 mL	0.4128 mL	2.0640 mL
100 mM	0.0206 mL	0.1032 mL	0.2064 mL	1.0320 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc