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DBCO-Sulfo-NHS ester sodium

Name: DBCO-Sulfo-NHS ester sodium
Brand: TargetMol
SKU: T15078
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15078Cas No. 1400191-52-7

DBCO-Sulfo-NHS ester sodium is a degradable ADC linker that can be used to synthesize ADC compounds.

DBCO-Sulfo-NHS ester sodium

🥰Excellent

Purity: 95.32%

Catalog No. T15078Cas No. 1400191-52-7

DBCO-Sulfo-NHS ester sodium is a degradable ADC linker that can be used to synthesize ADC compounds.

Pack Size	Price	Availability
1 mg	$38	In Stock
5 mg	$86	In Stock
10 mg	$126	In Stock
25 mg	$208	In Stock
50 mg	$312	In Stock
100 mg	$463	In Stock

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Batch Information

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Purity:95.32%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

DBCO-Sulfo-NHS ester sodium is a degradable ADC linker that can be used to synthesize ADC compounds.

Chemical Properties

Molecular Weight	532.5
Formula	C₂₅H₂₁N₂NaO₈S
Cas No.	1400191-52-7
Smiles	O=C(CCCCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)ON4C(CC(S(=O)([O-])=O)C4=O)=O.[Na+]
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 40 mg/mL (75.12 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.8779 mL	9.3897 mL	18.7793 mL	93.8967 mL
5 mM	0.3756 mL	1.8779 mL	3.7559 mL	18.7793 mL
10 mM	0.1878 mL	0.9390 mL	1.8779 mL	9.3897 mL
20 mM	0.0939 mL	0.4695 mL	0.9390 mL	4.6948 mL
50 mM	0.0376 mL	0.1878 mL	0.3756 mL	1.8779 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc