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DBCO-Sulfo-NHS ester sodium

Name: DBCO-Sulfo-NHS ester sodium
Brand: TargetMol
SKU: T15078
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15078Cas No. 1400191-52-7

DBCO-Sulfo-NHS ester sodium is a degradable ADC linker that can be used to synthesize ADC compounds.

DBCO-Sulfo-NHS ester sodium

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Purity: 95.32%

Catalog No. T15078Cas No. 1400191-52-7

DBCO-Sulfo-NHS ester sodium is a degradable ADC linker that can be used to synthesize ADC compounds.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$38	In Stock	In Stock
5 mg	$86	In Stock	In Stock
10 mg	$126	In Stock	In Stock
25 mg	$208	In Stock	In Stock
50 mg	$312	In Stock	In Stock
100 mg	$463	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:95.32%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

DBCO-Sulfo-NHS ester sodium is a degradable ADC linker that can be used to synthesize ADC compounds.

Chemical Properties

Molecular Weight	532.5
Formula	C₂₅H₂₁N₂NaO₈S
Cas No.	1400191-52-7
Smiles	O=C(CCCCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)ON4C(CC(S(=O)([O-])=O)C4=O)=O.[Na+]
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 40 mg/mL (75.12 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.8779 mL	9.3897 mL	18.7793 mL	93.8967 mL
5 mM	0.3756 mL	1.8779 mL	3.7559 mL	18.7793 mL
10 mM	0.1878 mL	0.9390 mL	1.8779 mL	9.3897 mL
20 mM	0.0939 mL	0.4695 mL	0.9390 mL	4.6948 mL
50 mM	0.0376 mL	0.1878 mL	0.3756 mL	1.8779 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc