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Anti-IL-18 Antibody (9W703) (Synonyms: interleukin 18, IL-1g, IL1F4, IL-18, IGIF)
Catalog No. TMAY-00297 Copy Product Info
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Anti-IL-18 Antibody (9W703) is a Rabbit antibody targeting IL-18. Anti-IL-18 Antibody (9W703) can be used in ELISA,ELISA(Cap).
Anti-IL-18 Antibody (9W703)
Copy Product Info🥰Excellent
Catalog No. TMAY-00297
Synonyms interleukin 18, IL-1g, IL1F4, IL-18, IGIF
Anti-IL-18 Antibody (9W703) is a Rabbit antibody targeting IL-18. Anti-IL-18 Antibody (9W703) can be used in ELISA,ELISA(Cap).
Anti-IL-18 Antibody
(9W703)
(9W703)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $93 | 7-10 days | 7-10 days | |
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IL-18 Antibody (9W703) is a Rabbit antibody targeting IL-18. Anti-IL-18 Antibody (9W703) can be used in ELISA,ELISA(Cap). |
| Synonyms | interleukin 18, IL-1g, IL1F4, IL-18, IGIF |
| Ig Type | Rabbit IgG |
| Clone | 9W703 |
| Reactivity | Human |
| Specificity | Human IL-18 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-18 (rh IL-18; TMPY-03381; Q14116; Met 1-Asp193). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. IL-18 is an IL-1-like cytokine that requires cleavage with caspase-1 to become active, was found to increase IgE production in a CD4+ T cell -, IL-4- and STAT6-dependent fashion. IL-18 and T cell receptor-mediated stimulation could induce naive CD4+ T cells to develop into IL-4-producing cells in vitro. Thus, caspase-1 and IL-18 may be critical in the regulation of IgE production in vivo, providing a potential therapeutic target for allergic disorders. IL-18 production in primary synovial cultures and purified synovial fibroblasts was, in turn, upregulated by TNF-α and IL-1β, suggesting that monokine expression can feedback to promote Th1 cell development in the synovial membrane. Besides, synergistic combinations of IL-18, IL-12, and IL-15 may be of importance in sustaining both Th1 responses and monokine production in RA.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human IL-18 protein (TMPY-03381) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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