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Anti-IL-25/IL17E Antibody (4K762)
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Catalog No. TMAY-03142
Alias interleukin 25
Anti-IL-25/IL17E Antibody (4K762) is a Rabbit antibody targeting IL-25/IL17E. Anti-IL-25/IL17E Antibody (4K762) can be used in ELISA.
Anti-IL-25/IL17E Antibody (4K762)
Anti-IL-25/IL17E Antibody (4K762)
😃Good
Catalog No. TMAY-03142Alias interleukin 25
Anti-IL-25/IL17E Antibody (4K762) is a Rabbit antibody targeting IL-25/IL17E. Anti-IL-25/IL17E Antibody (4K762) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-IL-25/IL17E Antibody (4K762) is a Rabbit antibody targeting IL-25/IL17E. Anti-IL-25/IL17E Antibody (4K762) can be used in ELISA. |
| Alias | interleukin 25 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4K762 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-25 (rM IL-25; TMPY-00855; NP_542767.1; Val 17-Ala 169). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells. IL-25 and IL-17, being members of the same cytokine family, play opposing roles in the pathogenesis of organ-specific autoimmunity. IL-25 promotes cell expansion and Th2 cytokine production when Th2 central memory cells are stimulated with thymic stromal lymphopoietin (TSLP)–activated dendritic cells (DCs), homeostatic cytokines, or T cell receptor for antigen triggering. Elevated expression of IL-25 and IL-25R transcripts was observed in asthmatic lung tissues and atopic dermatitis skin lesions, linking their possible roles with exacerbated allergic disorders. A plausible explanation that IL-25 produced by innate effector eosinophils and basophils may augment the allergic inflammation by enhancing the maintenance and functions of adaptive Th2 memory cells had been provided. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse IL-25 Protein (TMPY-00855) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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