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Methdilazine Hydrochloride

Name: Methdilazine Hydrochloride
Brand: TargetMol
SKU: T33319
Rating: 4.5 (1 reviews)

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Catalog No. T33319Cas No. 1229-35-2

Alias Tacaryl hydrochloride, MJ 5022 Hydrochloride, Methdilazine Hcl, Disyncran, Dilosyn, Bristaline

Methdilazine Hydrochloride (Bristaline) is a histamine H1 receptor antagonist used in the treatment of dermatologic conditions and for the relief of itching caused by allergies or rhinitis.

Methdilazine Hydrochloride

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Catalog No. T33319Alias Tacaryl hydrochloride, MJ 5022 Hydrochloride, Methdilazine Hcl, Disyncran, Dilosyn, BristalineCas No. 1229-35-2

Methdilazine Hydrochloride (Bristaline) is a histamine H1 receptor antagonist used in the treatment of dermatologic conditions and for the relief of itching caused by allergies or rhinitis.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$270	6-8 weeks	6-8 weeks
5 mg	$590	6-8 weeks	6-8 weeks
10 mg	$890	6-8 weeks	6-8 weeks
25 mg	$1,520	6-8 weeks	6-8 weeks
50 mg	$1,980	6-8 weeks	6-8 weeks
100 mg	$2,500	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	Methdilazine Hydrochloride (Bristaline) is a histamine H1 receptor antagonist used in the treatment of dermatologic conditions and for the relief of itching caused by allergies or rhinitis.
In vitro	Methdilazine Hydrochloride demonstrates inhibitory effects against various mycobacterial strains when applied at concentrations up to approximately 20 μg/mL for 18 hours, with observed minimum inhibitory concentrations (MICs) ranging between 5 and 15 μg/mL[1].
Synonyms	Tacaryl hydrochloride, MJ 5022 Hydrochloride, Methdilazine Hcl, Disyncran, Dilosyn, Bristaline

Chemical Properties

Molecular Weight	332.89
Formula	C₁₈H₂₁ClN₂S
Cas No.	1229-35-2
Smiles	Cl.S1C=2C=CC=CC2N(C=3C=CC=CC13)CC4CN(C)CC4
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight | store at 4°C | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (120.16 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 1.5 mg/mL (4.51 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0040 mL	15.0200 mL	30.0400 mL	150.1998 mL
5 mM	0.6008 mL	3.0040 mL	6.0080 mL	30.0400 mL
10 mM	0.3004 mL	1.5020 mL	3.0040 mL	15.0200 mL
20 mM	0.1502 mL	0.7510 mL	1.5020 mL	7.5100 mL
50 mM	0.0601 mL	0.3004 mL	0.6008 mL	3.0040 mL
100 mM	0.0300 mL	0.1502 mL	0.3004 mL	1.5020 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc