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Anti-IL-17RA Antibody-FITC (7E127)
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Catalog No. TMAY-01300F
Alias interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Anti-IL-17RA Antibody-FITC (7E127) is a FITC-conjugated Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody-FITC (7E127) can be used in FCM.
Anti-IL-17RA Antibody-FITC (7E127)
Anti-IL-17RA Antibody-FITC (7E127)
😃Good
Catalog No. TMAY-01300FAlias interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Anti-IL-17RA Antibody-FITC (7E127) is a FITC-conjugated Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody-FITC (7E127) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $104 | 7-10 days | |
| 100 T | $327 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-17RA Antibody-FITC (7E127) is a FITC-conjugated Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody-FITC (7E127) can be used in FCM. |
| Alias | interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 7E127 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human IL17RA(CD217) expression on human whole blood granulocytes. Cells were stained with FITC-conjugated anti-Human IL17RA(CD217). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17RA/IL-17RA/CD217 (rh IL17RA/IL-17RA/CD217; TMPY-01371; NP_055154.3; Met1-Trp320) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. |
| Conjucates | FITC |
| Others Formats | Unconjugated/APC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human IL17RA/IL-17RA/CD217 Protein (TMPY-01371) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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