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Anti-STAT6 Antibody (5D324)

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Catalog No. TMAY-02527
Alias STAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644

Anti-STAT6 Antibody (5D324) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (5D324) can be used in FCM.

Anti-STAT6 Antibody (5D324)

Anti-STAT6 Antibody (5D324)

😃Good
Catalog No. TMAY-02527Alias STAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644
Anti-STAT6 Antibody (5D324) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (5D324) can be used in FCM.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-STAT6 Antibody (5D324) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (5D324) can be used in FCM.
AliasSTAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644
Ig Type
Monoclonal Mouse IgG1
Clone
5D324
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human Stat6 expression on HT-29 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human Stat6, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human STAT6 (rh STAT6; TMPY-02603; P42226-1; Met1-Trp847). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSignal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-κB and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggests that the direct interaction between Stat6 and NF-κB may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-κB.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
FITC/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human STAT6 protein (TMPY-02603)
Antigen Species
Human
Biology Area
Apoptosis Transcription Factors and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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