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Anti-STAT6 Antibody (5D324) (Synonyms: STAT6C, STAT6B, signal transducer and activator of transcription 6, int...)

Name: Anti-STAT6 Antibody (5D324)
Brand: TargetMol
SKU: TMAY-02527
Rating: 4.5 (1 reviews)

Catalog No. TMAY-02527 Copy Product Info

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Anti-STAT6 Antibody (5D324) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (5D324) can be used in FCM.

Anti-STAT6 Antibody (5D324)

Copy Product Info

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Catalog No. TMAY-02527

Synonyms STAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644

Anti-STAT6 Antibody (5D324) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (5D324) can be used in FCM.

Anti-STAT6 Antibody
(5D324)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$198	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-STAT6 Antibody (5D324) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (5D324) can be used in FCM.
Synonyms	STAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644
Ig Type	Mouse IgG1
Clone	5D324
Reactivity	Human
Specificity	Human STAT6
Verified Activity	Flow cytometric analysis of Human Stat6 expression on HT-29 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human Stat6, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application	FCM
Recommended Dose	FCM: 1:25-1:100
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human STAT6 (rh STAT6; TMPY-02603; P42226-1; Met1-Trp847). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-κB and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggests that the direct interaction between Stat6 and NF-κB may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-κB.

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	FITC/PE
Antibody Types Available	3

Antigen Details

Immunogen	Recombinant Protein: Human STAT6 protein (TMPY-02603)
Antigen Species	Human
Biology Area	Apoptosis Transcription Factors and Regulators

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

D12S-1644D12S 1644

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