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EMCS

Name: EMCS
Brand: TargetMol
SKU: T14061
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14061Cas No. 55750-63-5

Alias 6-Maleimidohexanoic acid N-hydroxysuccinimide ester

EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective group in antibody drug conjugate.

EMCS

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Purity: 99.88%

Catalog No. T14061Alias 6-Maleimidohexanoic acid N-hydroxysuccinimide esterCas No. 55750-63-5

Pack Size	Price	Availability
200 mg	$35	In Stock
500 mg	$48	In Stock
1 g	$58	In Stock
5 g	$98	In Stock

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Purity:99.88%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective group in antibody drug conjugate.
In vitro	The peptides are first coupled with 6-Maleimidohexanoic acid N-hydroxysuccinimide ester, and then they are conjugated to the luciferase gene-containing Adenovirus vector as the carrier. [1]
Synonyms	6-Maleimidohexanoic acid N-hydroxysuccinimide ester

Chemical Properties

Molecular Weight	308.29
Formula	C₁₄H₁₆N₂O₆
Cas No.	55750-63-5
Smiles	O(C(CCCCCN1C(=O)C=CC1=O)=O)N2C(=O)CCC2=O
Relative Density.	1.40 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (145.97 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (16.22 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2437 mL	16.2185 mL	32.4370 mL	162.1850 mL
5 mM	0.6487 mL	3.2437 mL	6.4874 mL	32.4370 mL
10 mM	0.3244 mL	1.6218 mL	3.2437 mL	16.2185 mL
20 mM	0.1622 mL	0.8109 mL	1.6218 mL	8.1092 mL
50 mM	0.0649 mL	0.3244 mL	0.6487 mL	3.2437 mL
100 mM	0.0324 mL	0.1622 mL	0.3244 mL	1.6218 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc