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Anti-Phospho-CRK (Tyr221) Antibody (7E679)

😃Good
Catalog No. TMAS-00165
Alias Proto-oncogene c-Crk, p-CRK (Y221), p-CRK (Tyr221), CRKII, CRK (p-Y221), CRK (p-Tyr221), CRK, avian sarcoma virus CT10 (v-crk) oncogene homolog, Adapter molecule crk

Anti-Phospho-CRK (Tyr221) Antibody (7E679) is a Rabbit antibody targeting Phospho-CRK (Tyr221). Anti-Phospho-CRK (Tyr221) Antibody (7E679) can be used in ICC/IF, WB.

Anti-Phospho-CRK (Tyr221) Antibody (7E679)

Anti-Phospho-CRK (Tyr221) Antibody (7E679)

😃Good
Catalog No. TMAS-00165Alias Proto-oncogene c-Crk, p-CRK (Y221), p-CRK (Tyr221), CRKII, CRK (p-Y221), CRK (p-Tyr221), CRK, avian sarcoma virus CT10 (v-crk) oncogene homolog, Adapter molecule crk
Anti-Phospho-CRK (Tyr221) Antibody (7E679) is a Rabbit antibody targeting Phospho-CRK (Tyr221). Anti-Phospho-CRK (Tyr221) Antibody (7E679) can be used in ICC/IF, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$3697-10 days7-10 days
100 μL$6777-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-CRK (Tyr221) Antibody (7E679) is a Rabbit antibody targeting Phospho-CRK (Tyr221). Anti-Phospho-CRK (Tyr221) Antibody (7E679) can be used in ICC/IF, WB.
SynonymsProto-oncogene c-Crk, p-CRK (Y221), p-CRK (Tyr221), CRKII, CRK (p-Y221), CRK (p-Tyr221), CRK, avian sarcoma virus CT10 (v-crk) oncogene homolog, Adapter molecule crk
Ig Type
IgG
Clone
7E679
Reactivity
Human
Specificity
Phospho-CRK (Tyr221)
Verified Activity
Western blot analysis of Phospho-CrkII (Tyr221) expression in (1) K562 cell lysate treated with AP; (2) K562 cell lysate.
Application
Recommended Dose
ICC/IF: 1:50-1:200; WB: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesRabbit
PurificationAffinity-chromatography
AppearanceLiquid
FormulationSupplied in 10 mM phosphate buffered saline, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Research BackgroundThe Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized peptide: human CRK around the phosphorylation site of Y221
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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