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Anti-IL-12B Antibody (8D284) (Synonyms: interleukin 12B)
Catalog No. TMAY-00188 Copy Product Info
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Anti-IL-12B Antibody (8D284) is a Mouse antibody targeting IL-12B. Anti-IL-12B Antibody (8D284) can be used in ELISA(Cap).
Anti-IL-12B Antibody (8D284)
Copy Product Info🥰Excellent
Catalog No. TMAY-00188
Synonyms interleukin 12B
Anti-IL-12B Antibody (8D284) is a Mouse antibody targeting IL-12B. Anti-IL-12B Antibody (8D284) can be used in ELISA(Cap).
Anti-IL-12B Antibody
(8D284)
(8D284)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $94 | 7-10 days | 7-10 days | |
| 100 μL | $270 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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| Description | Anti-IL-12B Antibody (8D284) is a Mouse antibody targeting IL-12B. Anti-IL-12B Antibody (8D284) can be used in ELISA(Cap). |
| Synonyms | interleukin 12B |
| Ig Type | Mouse IgG1 |
| Clone | 8D284 |
| Reactivity | Human |
| Specificity | Human IL-12 p40/IL12B |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL12B / IL-12B (rh IL12B / IL-12B; TMPY-01045; NP_002178.2; Met1-Ser328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS with 0.02% Tween 80, pH 7.0 |
| Research Background | Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine is important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. IL12B/IL-12B associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine that functions in innate and adaptive immunity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human IL12B / IL-12B Protein (TMPY-01045) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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