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Anti-IL-12RB2 Antibody (9D131)
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Catalog No. TMAY-03105
Alias interleukin 12 receptor, β2, interleukin 12 receptor, beta 2
Anti-IL-12RB2 Antibody (9D131) is a Rabbit antibody targeting IL-12RB2. Anti-IL-12RB2 Antibody (9D131) can be used in ELISA.
Anti-IL-12RB2 Antibody (9D131)
Anti-IL-12RB2 Antibody (9D131)
😃Good
Catalog No. TMAY-03105Alias interleukin 12 receptor, β2, interleukin 12 receptor, beta 2
Anti-IL-12RB2 Antibody (9D131) is a Rabbit antibody targeting IL-12RB2. Anti-IL-12RB2 Antibody (9D131) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $94 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Mouse |
| Alias | interleukin 12 receptor, β2, interleukin 12 receptor, beta 2 |
| Ig Type | Rabbit IgG |
| Clone | 9D131 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL12RB2 (rM IL12RB2; TMPY-01767; NP_032380.1; Met1-Asn637). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-12 receptor subunit beta-2 (IL12RB2), also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, and IL-12RB2, is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. IL12RB2 belongs to the type I cytokine receptor family. The coexpression of IL12RB2 and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of IL12RB2 is up-regulated by IFN gamma in Th1 cells and plays a role in Th1 cell differentiation. The up-regulation of IL12RB2 is found to be associated with some infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. IL12RB2 promotes the proliferation of T-cells as well as NK cells. IL12RB2 induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse IL12RB2 protein (TMPY-01767) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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