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Anti-IL-12RB2 Antibody (9D131)

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Catalog No. TMAY-03105
Alias interleukin 12 receptor, β2, interleukin 12 receptor, beta 2

Anti-IL-12RB2 Antibody (9D131) is a Rabbit antibody targeting IL-12RB2. Anti-IL-12RB2 Antibody (9D131) can be used in ELISA.

Anti-IL-12RB2 Antibody (9D131)

Anti-IL-12RB2 Antibody (9D131)

😃Good
Catalog No. TMAY-03105Alias interleukin 12 receptor, β2, interleukin 12 receptor, beta 2
Anti-IL-12RB2 Antibody (9D131) is a Rabbit antibody targeting IL-12RB2. Anti-IL-12RB2 Antibody (9D131) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
20 μL$94 7-10 days
100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-IL-12RB2 Antibody (9D131) is a Rabbit antibody targeting IL-12RB2. Anti-IL-12RB2 Antibody (9D131) can be used in ELISA.
Aliasinterleukin 12 receptor, β2, interleukin 12 receptor, beta 2
Ig Type
Monoclonal Rabbit IgG
Clone
9D131
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL12RB2 (rM IL12RB2; TMPY-01767; NP_032380.1; Met1-Asn637).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundInterleukin-12 receptor subunit beta-2 (IL12RB2), also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, and IL-12RB2, is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. IL12RB2 belongs to the type I cytokine receptor family. The coexpression of IL12RB2 and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of IL12RB2 is up-regulated by IFN gamma in Th1 cells and plays a role in Th1 cell differentiation. The up-regulation of IL12RB2 is found to be associated with some infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. IL12RB2 promotes the proliferation of T-cells as well as NK cells. IL12RB2 induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse IL12RB2 protein (TMPY-01767)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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