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Anti-IL-28B Antibody (5K886)
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Catalog No. TMAY-03578
Alias interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B
Anti-IL-28B Antibody (5K886) is a Rabbit antibody targeting IL-28B. Anti-IL-28B Antibody (5K886) can be used in ELISA.
Anti-IL-28B Antibody (5K886)
Anti-IL-28B Antibody (5K886)
😃Good
Catalog No. TMAY-03578Alias interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B
Anti-IL-28B Antibody (5K886) is a Rabbit antibody targeting IL-28B. Anti-IL-28B Antibody (5K886) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-28B Antibody (5K886) is a Rabbit antibody targeting IL-28B. Anti-IL-28B Antibody (5K886) can be used in ELISA. |
| Alias | interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 5K886 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-28B / IFN-lambda-3 (rM IL-28B / IFN-lambda-3; TMPY-00454; NP_796370.1; Met1-Val193). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-28B (IL-28B) also known as Interferon lambda-3 and IFN-lambda-3, belongs to the type III interferon family of cytokines and are highly similar to IL-29. IL-28B belongs to the newly described interferon lambda (IFNλ) family of cytokines. IL-28B is a cytokine with immunomodulatory activity. It functions in Up-regulating MHC class I antigen expression. IL-28B displays potent antiviral activity and antitumor activity. This cytokine serves as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL-28B, like IL-12, is capable of robustly enhancing adaptive immunity. Moreover, we describe for the first time how IL-28B reduces regulatory T-cell populations during DNA vaccination, whereas IL-12 increases this cellular subset. We also show that IL-28B, unlike IL-12, can increase the percentage of splenic CD8+ T cells in vaccinated animals and that these cells are more granular and have higher antigen-specific cytolytic degranulation compared with cells taken from animals that received IL-12 as an adjuvant. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse IL-28B / IFN-lambda-3 Protein (TMPY-00454) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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