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Tibolone

Name: Tibolone
Brand: TargetMol
SKU: T4549
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4549Cas No. 5630-53-5

Alias tibolonum, tibolona

Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for the treatment of osteoporosis.

Tibolone

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Purity: 99.71%

Catalog No. T4549Alias tibolonum, tibolonaCas No. 5630-53-5

Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for the treatment of osteoporosis.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$40	In Stock	-
50 mg	$47	In Stock	-
1 mL x 10 mM (in DMSO)	$50	In Stock	-

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.71%

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COA

Product Introduction

Bioactivity

Description	Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for the treatment of osteoporosis.
Synonyms	tibolonum, tibolona

Chemical Properties

Molecular Weight	312.45
Formula	C₂₁H₂₈O₂
Cas No.	5630-53-5
Smiles	C[C@@H]1CC2=C(CCC(=O)C2)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]3(O)C#C)[C@H]12
Relative Density.	1.13g/cm3
Color	White
Appearance	solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 20 mg/mL (64.01 mM), Sonication is recommended.

H2O: insoluble

Ethanol: 2 mg/mL (6.4 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2005 mL	16.0026 mL	32.0051 mL	160.0256 mL
5 mM	0.6401 mL	3.2005 mL	6.4010 mL	32.0051 mL

DMSO

	1mg	5mg	10mg	50mg
10 mM	0.3201 mL	1.6003 mL	3.2005 mL	16.0026 mL
20 mM	0.1600 mL	0.8001 mL	1.6003 mL	8.0013 mL
50 mM	0.0640 mL	0.3201 mL	0.6401 mL	3.2005 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc