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Saringosterol

Name: Saringosterol
Brand: TargetMol
SKU: T68864
Price: 293 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T68864Cas No. 6901-60-6

Saringosterol is an antimicrobial phytosterol with inhibitory activity against Mycobacterium tuberculosis.

Saringosterol

🥰Excellent

Purity: 99.92%

Catalog No. T68864Cas No. 6901-60-6

Saringosterol is an antimicrobial phytosterol with inhibitory activity against Mycobacterium tuberculosis.

Pack Size	Price	Availability
1 mg	$293	In Stock
5 mg	$722	In Stock
10 mg	$987	In Stock
25 mg	$1,520	In Stock
50 mg	$1,980	In Stock

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Purity:99.92%

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COA LCMS HNMR

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Saringosterol is an antimicrobial phytosterol with inhibitory activity against Mycobacterium tuberculosis.
In vitro	In RAW264.7 macrophages, Saringosterol (2-10 μM, 24 h) significantly inhibits LPS-induced production of NO and IL-6, indicating anti-inflammatory activity. In ABCA1 expression assays, Saringosterol (5 μM) activates the LXR signaling pathway and upregulates ABCA1 and ABCG1 gene expression[1].
In vivo	In a high-fat diet-induced Alzheimer’s disease mouse model, intraperitoneal injection of Saringosterol (10 mg/kg, every 2 days for 8 weeks) significantly increased ABCA1 and APOE expression in the hippocampus, enhanced cholesterol efflux, and improved learning and memory[1].

Chemical Properties

Molecular Weight	428.69
Formula	C₂₉H₄₈O₂
Cas No.	6901-60-6
Smiles	C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(C(C)C)(C=C)O)C)[H])[H]

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc