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AF488 5-SDP ester (Synonyms: Alexa Fluor 488 5-SDP Ester)
Catalog No. T212880 Copy Product Info
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Alexa Fluor 488 5-SDP Ester is an amine-reactive green fluorescent dye with a sulfonyl dichlorophenol (SDP) ester group, which selectively reacts with primary amines on proteins, peptides, or other biomolecules to form stable amide bonds. The SDP ester exhibits excellent hydrolytic stability, outperforming conventional NHS esters in aqueous and buffered solutions, allowing precise control of labeling reactions. Amide bonds formed via SDP esters are comparable in strength to those formed by NHS esters, ensuring stable and reliable conjugates.
AF488 5-SDP ester
Copy Product Info😃Good
Catalog No. T212880
Synonyms Alexa Fluor 488 5-SDP Ester
Alexa Fluor 488 5-SDP Ester is an amine-reactive green fluorescent dye with a sulfonyl dichlorophenol (SDP) ester group, which selectively reacts with primary amines on proteins, peptides, or other biomolecules to form stable amide bonds. The SDP ester exhibits excellent hydrolytic stability, outperforming conventional NHS esters in aqueous and buffered solutions, allowing precise control of labeling reactions. Amide bonds formed via SDP esters are comparable in strength to those formed by NHS esters, ensuring stable and reliable conjugates.
AF488 5-SDP ester
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Product Introduction
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Chemical Properties
Storage & Solubility Information
| Description | Alexa Fluor 488 5-SDP Ester is an amine-reactive green fluorescent dye with a sulfonyl dichlorophenol (SDP) ester group, which selectively reacts with primary amines on proteins, peptides, or other biomolecules to form stable amide bonds. The SDP ester exhibits excellent hydrolytic stability, outperforming conventional NHS esters in aqueous and buffered solutions, allowing precise control of labeling reactions. Amide bonds formed via SDP esters are comparable in strength to those formed by NHS esters, ensuring stable and reliable conjugates. |
| Synonyms | Alexa Fluor 488 5-SDP Ester |
| Storage | Keep away from direct sunlight | Store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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