Shopping Cart

Remove All
Your shopping cart is currently empty

Cefoxitin

Name: Cefoxitin
Brand: TargetMol
SKU: T20643
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T20643Cas No. 35607-66-0

Alias Rephoxitin, Cefoxitinum

Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and Gram-positive bacteria, and is commonly used in abdominal cavity infections, pelvic infections, and certain types of gynecological infections, and is highly effective against anaerobic bacteria.

Cefoxitin

🥰Excellent

Purity: 99.89%

Catalog No. T20643Alias Rephoxitin, CefoxitinumCas No. 35607-66-0

Pack Size	Price	Availability
50 mg	$30	In Stock
100 mg	$40	In Stock
500 mg	$89	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.89%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and Gram-positive bacteria, and is commonly used in abdominal cavity infections, pelvic infections, and certain types of gynecological infections, and is highly effective against anaerobic bacteria.
Targets&IC50	PBP4:0.14 μg/mL, PBP2a:0.72 μg/mL, PBP2b:0.19 μg/mL, PBP5:0.19 μg/mL, PBP3:1.04 μg/mL
In vitro	Cefoxitin demonstrates effective antimicrobial properties against Gram-positive bacteria, with minimum inhibitory concentrations (MICs) spanning from 1-6 μg/mL for various Gram-positive pathogens[1]. Furthermore, at a concentration of 1.25 µM/mL, Cefoxitin exhibits potent bactericidal activity against B. burgdorferi[2].
In vivo	Cefoxitin administration at a dose of 20 mg/kg via intraperitoneal injection for 5 consecutive days demonstrates effective eradication of B. burgdorferi in the C3H/HeN mouse model.[2]
Synonyms	Rephoxitin, Cefoxitinum

Chemical Properties

Molecular Weight	427.45
Formula	C₁₆H₁₇N₃O₇S₂
Cas No.	35607-66-0
Smiles	[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@]2(NC(=O)Cc1cccs1)OC)C(O)=O
Relative Density.	1.63 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90.0 mg/mL (210.6 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (7.72 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3395 mL	11.6973 mL	23.3945 mL	116.9727 mL
5 mM	0.4679 mL	2.3395 mL	4.6789 mL	23.3945 mL
10 mM	0.2339 mL	1.1697 mL	2.3395 mL	11.6973 mL
20 mM	0.1170 mL	0.5849 mL	1.1697 mL	5.8486 mL
50 mM	0.0468 mL	0.2339 mL	0.4679 mL	2.3395 mL
100 mM	0.0234 mL	0.1170 mL	0.2339 mL	1.1697 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc