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Cefiderocol

Name: Cefiderocol
Brand: TargetMol
SKU: T7585
Rating: 4.5 (1 reviews)

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Catalog No. T7585Cas No. 1225208-94-5

Alias S-649266, S649266, RSC649266, RSC 649266, GSK269626, GSK 269626

Cefiderocol (S-649266) is a novel iron-siderophore-cephalosporin conjugate with antibacterial activity, inhibiting aerobic Gram-negative bacteria, used in bacterial infection research.

Cefiderocol

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Purity: 98.46%

Catalog No. T7585Alias S-649266, S649266, RSC649266, RSC 649266, GSK269626, GSK 269626Cas No. 1225208-94-5

Cefiderocol (S-649266) is a novel iron-siderophore-cephalosporin conjugate with antibacterial activity, inhibiting aerobic Gram-negative bacteria, used in bacterial infection research.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$193	Inquiry	Inquiry
5 mg	$488	In Stock	-
10 mg	$737	In Stock	-
25 mg	$1,570	Inquiry	Inquiry
50 mg	Preferential	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.46%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Cefiderocol (S-649266) is a novel iron-siderophore-cephalosporin conjugate with antibacterial activity, inhibiting aerobic Gram-negative bacteria, used in bacterial infection research.
In vitro	Cefiderocol showed excellent antimicrobial activity against CRAB.
Synonyms	S-649266, S649266, RSC649266, RSC 649266, GSK269626, GSK 269626

Chemical Properties

Molecular Weight	752.22
Formula	C₃₀H₃₄ClN₇O₁₀S₂
Cas No.	1225208-94-5
Smiles	C([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC(C(O)=O)(C)C)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]4(CCNC(=O)C5=C(Cl)C(O)=C(O)C=C5)CCCC4)[H]
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture,The compound is unstable in solution. Please use soon | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (106.35 mM), Sonication is recommended. The compound is unstable in solution. Please use soon.

H2O: 1 mg/mL (1.33 mM), Sonication is recommended. The compound is unstable in solution. Please use soon.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (4.39 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3294 mL	6.6470 mL	13.2940 mL	66.4699 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.2659 mL	1.3294 mL	2.6588 mL	13.2940 mL
10 mM	0.1329 mL	0.6647 mL	1.3294 mL	6.6470 mL
20 mM	0.0665 mL	0.3323 mL	0.6647 mL	3.3235 mL
50 mM	0.0266 mL	0.1329 mL	0.2659 mL	1.3294 mL
100 mM	0.0133 mL	0.0665 mL	0.1329 mL	0.6647 mL

Calculator

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Dilution Calculator
Reconstitution Calculator
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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Cefiderocol

Cefiderocol

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Batch Information

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Product Introduction

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In Vivo Formulation Calculator (Clear solution)

Dose Conversion

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