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Cefiderocol

🥰Excellent
Catalog No. T7585Cas No. 1225208-94-5
Alias S-649266, S649266, RSC649266, RSC 649266, GSK269626, GSK 269626

Cefiderocol (S-649266) is a novel iron-siderophore-cephalosporin conjugate with antibacterial activity, inhibiting aerobic Gram-negative bacteria, used in bacterial infection research.

Cefiderocol

Cefiderocol

🥰Excellent
Purity: 98.46%
Catalog No. T7585Alias S-649266, S649266, RSC649266, RSC 649266, GSK269626, GSK 269626Cas No. 1225208-94-5
Cefiderocol (S-649266) is a novel iron-siderophore-cephalosporin conjugate with antibacterial activity, inhibiting aerobic Gram-negative bacteria, used in bacterial infection research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$193-In Stock
5 mg$488In StockIn Stock
10 mg$737In StockIn Stock
25 mg$1,570-In Stock
50 mgPreferential-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.46%
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Product Introduction

Bioactivity
Description
Cefiderocol (S-649266) is a novel iron-siderophore-cephalosporin conjugate with antibacterial activity, inhibiting aerobic Gram-negative bacteria, used in bacterial infection research.
In vitro
Cefiderocol showed excellent antimicrobial activity against CRAB.
SynonymsS-649266, S649266, RSC649266, RSC 649266, GSK269626, GSK 269626
Chemical Properties
Molecular Weight752.22
FormulaC30H34ClN7O10S2
Cas No.1225208-94-5
SmilesC([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC(C(O)=O)(C)C)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]4(CCNC(=O)C5=C(Cl)C(O)=C(O)C=C5)CCCC4)[H]
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (106.35 mM), Sonication is recommended. The compound is unstable in solution. Please use soon.
H2O: 1 mg/mL (1.33 mM), Sonication is recommended. The compound is unstable in solution. Please use soon.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (4.39 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.3294 mL6.6470 mL13.2940 mL66.4699 mL
DMSO
1mg5mg10mg50mg
5 mM0.2659 mL1.3294 mL2.6588 mL13.2940 mL
10 mM0.1329 mL0.6647 mL1.3294 mL6.6470 mL
20 mM0.0665 mL0.3323 mL0.6647 mL3.3235 mL
50 mM0.0266 mL0.1329 mL0.2659 mL1.3294 mL
100 mM0.0133 mL0.0665 mL0.1329 mL0.6647 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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