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Anti-IL-21 Antibody (4F183) (Synonyms: interleukin 21)

Catalog No. TMAY-00991 Copy Product Info
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Anti-IL-21 Antibody (4F183) is a Mouse antibody targeting IL-21. Anti-IL-21 Antibody (4F183) can be used in ELISA,ELISA(Cap).

Anti-IL-21 Antibody (4F183)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00991
Synonyms interleukin 21

Anti-IL-21 Antibody (4F183) is a Mouse antibody targeting IL-21. Anti-IL-21 Antibody (4F183) can be used in ELISA,ELISA(Cap).

Anti-IL-21 Antibody
(4F183)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$697-10 days7-10 days
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-21 Antibody (4F183) is a Mouse antibody targeting IL-21. Anti-IL-21 Antibody (4F183) can be used in ELISA,ELISA(Cap).
Synonymsinterleukin 21
Ig Type
Mouse IgG1
Clone
4F183
Reactivity
Human
Specificity
Human IL-21
Application
Recommended Dose
ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-21 (rh IL-21; TMPY-01963; Q9HBE4-1; Gln30-Ser162). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IL-21 Protein (TMPY-01963)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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