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Siltuximab (Synonyms: CNTO-328)
Catalog No. T76978 Copy Product Info
Purity: 95%
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Siltuximab(CNTO-328) is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.
Siltuximab
Copy Product Info🥰Excellent
Catalog No. T76978
Synonyms CNTO-328
Siltuximab(CNTO-328) is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.
Siltuximab
Cas No. 541502-14-1
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $178 | In Stock | In Stock | |
| 5 mg | $439 | In Stock | In Stock | |
| 10 mg | $648 | - | In Stock | |
| 25 mg | $987 | - | In Stock | |
| 50 mg | $1,390 | - | In Stock | |
| 100 mg | $1,870 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Siltuximab(CNTO-328) is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19. |
| In vivo | In xenograft mouse models, Siltuximab, when administered through intraperitoneal injection at a dosage of 10 mg/kg three times per week, inhibits the growth of lung cancer cells[1]. Furthermore, in a xenograft model, the growth of MCF-7 tumors is inhibited by Siltuximab with intraperitoneal injections at a dose of 20 mg/kg twice per week for 6 weeks[3]. |
| Synonyms | CNTO-328 |
| Reactivity | Human |
| Verified Activity | Immobilized Human IL-6 Protein (His) at 2 μg/mL (30 μL/well) can bind Siltuximab. The EC50 is 58.73 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-6/IFNb2 |
| Molecular Weight | 144.98 kDa |
| Cas No. | 541502-14-1 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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