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Anti-IL-15 Antibody (4S411) is a Rabbit antibody targeting IL-15. Anti-IL-15 Antibody (4S411) can be used in ELISA(Cap).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $94 | 7-10 days | |
100 μL | $269 | 7-10 days |
Description | Anti-IL-15 Antibody (4S411) is a Rabbit antibody targeting IL-15. Anti-IL-15 Antibody (4S411) can be used in ELISA(Cap). |
Alias | interleukin 15, IL-15 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 4S411 |
Reactivity | Human |
Application | ELISA(Cap) |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL15 / IL-15 / Interleukin 15 (rh IL15 / IL-15 / Interleukin 15; TMPY-04049; NP_000576.1; Asn49-Ser162). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
Research Background | The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietic receptor subunits and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively, spliced transcript variants of this gene have been reported.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | Unconjugated |
Immunogen | Recombinant Human IL15 / IL-15 / Interleukin 15 Protein (TMPY-04049) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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