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Anti-IFN gamma Antibody (9I367)
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Catalog No. TMAY-02016
Alias interferon, γ, interferon, gamma, IFN γ
Anti-IFN gamma Antibody (9I367) is a Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody (9I367) can be used in FCM.
Anti-IFN gamma Antibody (9I367)
Anti-IFN gamma Antibody (9I367)
😃Good
Catalog No. TMAY-02016Alias interferon, γ, interferon, gamma, IFN γ
Anti-IFN gamma Antibody (9I367) is a Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody (9I367) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-IFN gamma Antibody (9I367) is a Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody (9I367) can be used in FCM. |
| Alias | interferon, γ, interferon, gamma, IFN γ |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9I367 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human IFN-γ expression on human peripheral blood lymphocytes. Human peripheral blood mononulcear cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human IFN-γ, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human IFN gamma / IFNG (rh IFN gamma / IFNG; TMPY-01714; NP_000610.2; Met1-Gln166). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Others Formats | APC/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human IFN gamma / IFNG Protein (TMPY-01714) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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