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Anti-IL-17RB Antibody (4T989)
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Catalog No. TMAY-02472
Alias interleukin 17 receptor B
Anti-IL-17RB Antibody (4T989) is a Mouse antibody targeting IL-17RB. Anti-IL-17RB Antibody (4T989) can be used in ELISA.
Anti-IL-17RB Antibody (4T989)
Anti-IL-17RB Antibody (4T989)
😃Good
Catalog No. TMAY-02472Alias interleukin 17 receptor B
Anti-IL-17RB Antibody (4T989) is a Mouse antibody targeting IL-17RB. Anti-IL-17RB Antibody (4T989) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
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Antigen Details
Chemical Properties
| Description | Anti-IL-17RB Antibody (4T989) is a Mouse antibody targeting IL-17RB. Anti-IL-17RB Antibody (4T989) can be used in ELISA. |
| Alias | interleukin 17 receptor B |
| Ig Type | Monoclonal Mouse IgG2b |
| Clone | 4T989 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17BR / IL17RB / IL-17 Receptor B (rh IL17BR / IL17RB / IL-17 Receptor B; TMPY-04052; NP_061195.2; Met1-Gly289). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGFbeta. Overexpression of IL17RB is associated with poor prognosis and the short survival of breast cancer patients.IL17RB/IL17B signaling triggers a substantial increase in cell growth, proliferation, and migration through the activation of NF-kappaB as well as the up-regulation of the Bcl-2. IL17RB may be the only gene expressed in CD4+ T cells whose transcript measurement is correlated with the variation in IgE level in asthmatics. Diseases associated with IL17RB include Chronic Mucocutaneous Candidiasis and Seborrheic Infantile Dermatitis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human IL17BR / IL17RB / IL-17 Receptor B Protein (TMPY-04052) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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