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Anti-GRM7 Antibody (6J762) (Synonyms: OTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MG...)

Catalog No. TMAC-01722 Copy Product Info
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Anti-GRM7 Antibody (6J762) is a Mouse antibody targeting GRM7. Anti-GRM7 Antibody (6J762) can be used in FCM,ICC,WB.

Anti-GRM7 Antibody (6J762)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01722
Synonyms OTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MGLU7, Metabotropic glutamate receptor 7, GRM7_HUMAN, GRM 7, GPRC1G, Glutamate receptor metabotropic 7, GLUR7, FLJ40498

Anti-GRM7 Antibody (6J762) is a Mouse antibody targeting GRM7. Anti-GRM7 Antibody (6J762) can be used in FCM,ICC,WB.

Anti-GRM7 Antibody
(6J762)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GRM7 Antibody (6J762) is a Mouse antibody targeting GRM7. Anti-GRM7 Antibody (6J762) can be used in FCM,ICC,WB.
SynonymsOTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MGLU7, Metabotropic glutamate receptor 7, GRM7_HUMAN, GRM 7, GPRC1G, Glutamate receptor metabotropic 7, GLUR7, FLJ40498
Clone
6J762
Reactivity
Human
Verified Activity
1. Western blot analysis of GRM7 on human GRM7 recombinant protein using anti-GRM7 antibody at 1/1,000 dilution.
2. Western blot analysis of GRM7 on HEK293 (1) and GRM7-hIgGFc transfected HEK293 (2) cell lysate using anti-GRM7 antibody at 1/1,000 dilution.
3. ICC staining GRM7 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining GRM7 (green) and Actin filaments (red) in SMMC-7721 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Flow cytometric analysis of SH-SY5Y cells with GRM7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundL-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 102 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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