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Anti-GRM7 Antibody (6J762)
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Catalog No. TMAC-01722
Alias OTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MGLU7, Metabotropic glutamate receptor 7, GRM7_HUMAN, GRM 7, GPRC1G, Glutamate receptor metabotropic 7, GLUR7, FLJ40498
Anti-GRM7 Antibody (6J762) is a Mouse antibody targeting GRM7. Anti-GRM7 Antibody (6J762) can be used in WB,ICC,FCM.
Anti-GRM7 Antibody (6J762)
Anti-GRM7 Antibody (6J762)
😃Good
Catalog No. TMAC-01722Alias OTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MGLU7, Metabotropic glutamate receptor 7, GRM7_HUMAN, GRM 7, GPRC1G, Glutamate receptor metabotropic 7, GLUR7, FLJ40498
Anti-GRM7 Antibody (6J762) is a Mouse antibody targeting GRM7. Anti-GRM7 Antibody (6J762) can be used in WB,ICC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $427 | 7-10 days |
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| Description | Anti-GRM7 Antibody (6J762) is a Mouse antibody targeting GRM7. Anti-GRM7 Antibody (6J762) can be used in WB,ICC,FCM. |
| Synonyms | OTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MGLU7, Metabotropic glutamate receptor 7, GRM7_HUMAN, GRM 7, GPRC1G, Glutamate receptor metabotropic 7, GLUR7, FLJ40498 |
| Clone | 6J762 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of GRM7 on human GRM7 recombinant protein using anti-GRM7 antibody at 1/1,000 dilution. 2. Western blot analysis of GRM7 on HEK293 (1) and GRM7-hIgGFc transfected HEK293 (2) cell lysate using anti-GRM7 antibody at 1/1,000 dilution. 3. ICC staining GRM7 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining GRM7 (green) and Actin filaments (red) in SMMC-7721 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of SH-SY5Y cells with GRM7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 102 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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