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Anti-IL-12RB1 Antibody (7W278)
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Catalog No. TMAY-01979
Alias ENPP2, ectonucleotide pyrophosphatase/phosphodiesterase 2, Autotaxin
Anti-IL-12RB1 Antibody (7W278) is a Mouse antibody targeting IL-12RB1. Anti-IL-12RB1 Antibody (7W278) can be used in ELISA.
Anti-IL-12RB1 Antibody (7W278)
Anti-IL-12RB1 Antibody (7W278)
😃Good
Catalog No. TMAY-01979Alias ENPP2, ectonucleotide pyrophosphatase/phosphodiesterase 2, Autotaxin
Anti-IL-12RB1 Antibody (7W278) is a Mouse antibody targeting IL-12RB1. Anti-IL-12RB1 Antibody (7W278) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-12RB1 Antibody (7W278) is a Mouse antibody targeting IL-12RB1. Anti-IL-12RB1 Antibody (7W278) can be used in ELISA. |
| Alias | ENPP2, ectonucleotide pyrophosphatase/phosphodiesterase 2, Autotaxin |
| Ig Type | Monoclonal Mouse IgG2b |
| Clone | 7W278 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL12RB1 (rh IL12RB1; TMPY-01701; NP_005526.1; Met1-Glu540). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin 12 receptor, beta 1 is also known as IL-12 receptor beta component, IL-12R subunit beta-1, and CD212 antigen (CD212). IL12RB1(CD212) is a subunit of the interleukin 12 receptor. IL12RB1(CD212) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukin 12 (IL12) with a low affinity and is thought to be a part of the IL12 receptor complex. IL12RB1(CD212) forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of IL12RB1 and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. IL12RB1(CD212) Functions as an interleukin receptor that binds interleukin-12 with low affinity and is involved in IL12 transduction. It is associated with IL12RB2 it forms a functional, high-affinity receptor for IL12. IL12RB1(CD212) associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human IL12RB1 Protein (TMPY-01701) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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