Diclofenac methyl ester

Name: Diclofenac methyl ester
Brand: TargetMol
SKU: T37482
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T37482Cas No. 15307-78-5

Diclofenac methyl ester is a hydrophobic prodrug form of diclofenac which is a non-steroidal anti-inflammatory drug (NSAID). Diclofenac methyl ester is more soluble than diclofenac acid in isopropylmyristate but with higher toxicity.

Diclofenac methyl ester

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Purity: 98.04%

Catalog No. T37482Cas No. 15307-78-5

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$35	In Stock	In Stock
25 mg	$56	In Stock	In Stock
50 mg	$81	In Stock	In Stock
100 mg	$118	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:98.04%

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COA LCMS

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	310.18
Formula	C₁₅H₁₃Cl₂NO₂
Cas No.	15307-78-5
Smiles	COC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl
Relative Density.	1.335g/cm3

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMF:PBS (pH 7.2) (1:3): 0.25 mg/mL (0.81 mM), Sonication is recommended. DMF: 10 mg/mL (32.24 mM), Sonication is recommended. DMSO: 5 mg/mL (16.12 mM), Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc