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LGD-2941
(Synonyms: LGD2941, LGD 2941) Copy Product Info
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Synonyms: LGD2941, LGD 2941
Catalog No. T27826 Copy Product Info
Purity: 99.90%
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LGD-2941 is a non-steroidal selective androgen receptor modulator (SARM) that selectively agonizes the androgen receptor to exert anabolic effects and is used in endocrine-related research on hypogonadism and osteoporosis.
Cas No. 847235-85-2
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $413 | - | In Stock | |
| 5 mg | $982 | - | In Stock | |
| 10 mg | $1,320 | - | In Stock | |
| 25 mg | $1,970 | - | In Stock | |
| 50 mg | $2,580 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.90%
Appearance:Solid
Color:Yellow
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Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | LGD-2941 is a non-steroidal selective androgen receptor modulator (SARM) that selectively agonizes the androgen receptor to exert anabolic effects and is used in endocrine-related research on hypogonadism and osteoporosis. |
| In vivo | Method: Twenty-four male cynomolgus monkeys were divided into four groups of six and treated for 90 days; the LGD-2941 group received 1 mg/kg daily. Whole-blood samples collected before treatment and on days 16 and 90 were analyzed for 37 candidate genes by qRT-PCR. Result: LGD-2941 significantly altered six of the 37 genes, including CD30L, Fas, TNFR1, TNFR2, IL-12B and IL-15, indicating a measurable androgen-receptor-ligand gene-expression signature in whole blood.[1] |
| Synonyms | LGD2941, LGD 2941 |
| Molecular Weight | 394.31 |
| Formula | C17H16F6N2O2 |
| Cas No. | 847235-85-2 |
| Smiles | [C@@H](C(F)(F)F)(O)[C@@]1(N([C@H](C)CC1)C=2C=C3C(=CC2)NC(=O)C=C3C(F)(F)F)[H] |
| Relative Density. | 1.422 g/cm3 (Predicted) |
| Storage | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Product Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: LGD-2941 chemical structure | LGD-2941 in vivo | LGD-2941 formula | LGD-2941 molecular weight
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