Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 123.00 | |
5 mg | 35 days | $ 950.00 |
Description | Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization. |
Molecular Weight | 386.51 |
Formula | C19H26N6OS |
CAS No. | 361431-33-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL
DMF: 30 mg/mL
Ethanol: 20 mg/mL
DMSO: 30 mg/mL
You can also refer to dose conversion for different animals. More
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Diminutol 361431-33-6 inhibitor inhibit