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YTK-105

🥰Excellent
Catalog No. T87944Cas No. 774192-20-0
Alias YTK105, YTK 105

YTK-105 is a ligand targeting autophagy that binds to p62.

YTK-105

YTK-105

🥰Excellent
Purity: 98.31%
Catalog No. T87944Alias YTK105, YTK 105Cas No. 774192-20-0
YTK-105 is a ligand targeting autophagy that binds to p62.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$30-In Stock
5 mg$64In StockIn Stock
10 mg$98In StockIn Stock
25 mg$198In StockIn Stock
50 mg$333-In Stock
100 mg$533-In Stock
200 mg$759-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.31%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
YTK-105 is a ligand targeting autophagy that binds to p62.
In vitro
YTK-105 is a ligand for the p62-ZZ structural domain that activates p62-dependent selective macroautophagy.YTK-105 can be used in the design of AUTOTAC.
SynonymsYTK105, YTK 105
Chemical Properties
Molecular Weight257.33
FormulaC16H19NO2
Cas No.774192-20-0
SmilesOCCNCC=1C=CC=C(OCC=2C=CC=CC2)C1
Relative Density.no data available
ColorYellow
AppearanceOil
Storage & Solubility Information
Storagestore at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 150 mg/mL (582.91 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8861 mL19.4303 mL38.8606 mL194.3030 mL
5 mM0.7772 mL3.8861 mL7.7721 mL38.8606 mL
10 mM0.3886 mL1.9430 mL3.8861 mL19.4303 mL
20 mM0.1943 mL0.9715 mL1.9430 mL9.7152 mL
50 mM0.0777 mL0.3886 mL0.7772 mL3.8861 mL
100 mM0.0389 mL0.1943 mL0.3886 mL1.9430 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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