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YTK-105

😃Good
Catalog No. T87944Cas No. 774192-20-0
Alias YTK105, YTK 105

YTK-105 is a ligand targeting autophagy that binds to p62.

YTK-105

YTK-105

😃Good
Purity: 98.31%
Catalog No. T87944Alias YTK105, YTK 105Cas No. 774192-20-0
YTK-105 is a ligand targeting autophagy that binds to p62.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$38-In Stock
5 mg$60In StockIn Stock
10 mg$98In StockIn Stock
25 mg$197In StockIn Stock
50 mg$318-In Stock
100 mg$497-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.31%
Appearance:Oil
Color:Yellow
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Product Introduction

Bioactivity
Description
YTK-105 is a ligand targeting autophagy that binds to p62.
In vitro
YTK-105 is a ligand for the p62-ZZ structural domain that activates p62-dependent selective macroautophagy.YTK-105 can be used in the design of AUTOTAC.
SynonymsYTK105, YTK 105
Chemical Properties
Molecular Weight257.33
FormulaC16H19NO2
Cas No.774192-20-0
SmilesOCCNCC=1C=CC=C(OCC=2C=CC=CC2)C1
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 150 mg/mL (582.91 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8861 mL19.4303 mL38.8606 mL194.3030 mL
5 mM0.7772 mL3.8861 mL7.7721 mL38.8606 mL
10 mM0.3886 mL1.9430 mL3.8861 mL19.4303 mL
20 mM0.1943 mL0.9715 mL1.9430 mL9.7152 mL
50 mM0.0777 mL0.3886 mL0.7772 mL3.8861 mL
100 mM0.0389 mL0.1943 mL0.3886 mL1.9430 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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