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Biotin alkyne

Name: Biotin alkyne
Brand: TargetMol
SKU: T66674
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T66674Cas No. 773888-45-2

Biotin alkyne is a PEG-based PROTAC linker for PROTAC synthesis, whose alkyne group undergoes click chemistry reactions with azide-containing molecules.

Biotin alkyne

🥰Excellent

Purity: 99.667%

Catalog No. T66674Cas No. 773888-45-2

Biotin alkyne is a PEG-based PROTAC linker for PROTAC synthesis, whose alkyne group undergoes click chemistry reactions with azide-containing molecules.

Pack Size	Price	Availability
25 mg	$34	In Stock
50 mg	$47	In Stock
100 mg	$68	In Stock
500 mg	$162	In Stock

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Purity:99.667%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

Biotin alkyne is a PEG-based PROTAC linker for PROTAC synthesis, whose alkyne group undergoes click chemistry reactions with azide-containing molecules.

Chemical Properties

Molecular Weight	281.37
Formula	C₁₃H₁₉N₃O₂S
Cas No.	773888-45-2
Smiles	C#CCNC(=O)CCCC[C@H]1[C@]2([H])[C@@](CS1)([H])NC(=O)N2
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200.00 mg/mL (710.81 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5540 mL	17.7702 mL	35.5404 mL	177.7020 mL
5 mM	0.7108 mL	3.5540 mL	7.1081 mL	35.5404 mL
10 mM	0.3554 mL	1.7770 mL	3.5540 mL	17.7702 mL
20 mM	0.1777 mL	0.8885 mL	1.7770 mL	8.8851 mL
50 mM	0.0711 mL	0.3554 mL	0.7108 mL	3.5540 mL
100 mM	0.0355 mL	0.1777 mL	0.3554 mL	1.7770 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc