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Hydramethylnon
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Catalog No. T19816Cas No. 67485-29-4
Alias Matox, Combat, Amdro, AC-217300, AC217300, AC 217300
Hydramethylnon (AC217300) is an insecticide primarily. Hydramethylnon is used for fire ants.
Hydramethylnon
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Purity: 99.89%
Catalog No. T19816Alias Matox, Combat, Amdro, AC-217300, AC217300, AC 217300Cas No. 67485-29-4
Hydramethylnon (AC217300) is an insecticide primarily. Hydramethylnon is used for fire ants.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $50 | In Stock | In Stock | |
| 10 mg | $70 | In Stock | In Stock | |
| 25 mg | $114 | In Stock | In Stock | |
| 50 mg | $167 | In Stock | In Stock | |
| 100 mg | $248 | In Stock | In Stock | |
| 500 mg | $535 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $72 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
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Purity:99.89%
Appearance:Solid
Color:Yellow
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Product Introduction
Hydramethylnon AI Summary
Hydramethylnon exhibits significant insecticidal activity against a range of Blattella germanica (German cockroach) strains, including both insecticide-resistant and insecticide-susceptible populations at various instar stages. It demonstrates a faster effect on second instar insects compared to fifth instar insects, with consistent efficacy across both resistant and susceptible strains. Additionally, Hydramethylnon functions as an agonist and antagonist for multiple receptors, including retinoid X receptor alpha, androgen receptor, glucocorticoid receptor, thyroid hormone receptor beta, and several others, indicating a broad range of bioactivities. The compound also effectively inhibits the efflux of Doxorubicin in MDR1-expressing B16/F10 cells, achieving an inhibition rate of over 80.0%. Furthermore, it acts as an inhibitor of cytochrome c oxidase in Drosophila melanogaster mitochondria, with an IC50 of 480,000.0 nM in resistant strains and 470,000.0 nM in susceptible strains, suggesting its potential to disrupt mitochondrial function..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Hydramethylnon (AC217300) is an insecticide primarily. Hydramethylnon is used for fire ants. |
| Synonyms | Matox, Combat, Amdro, AC-217300, AC217300, AC 217300 |
| Molecular Weight | 494.48 |
| Formula | C25H24F6N4 |
| Cas No. | 67485-29-4 |
| Smiles | CC1(C)CNC(NC1)=NN=C(\C=C\c1ccc(cc1)C(F)(F)F)/C=C/c1ccc(cc1)C(F)(F)F |
| Relative Density. | 1.67. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 65 mg/mL (131.45 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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