Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-O-C3-acid is a chemically derived conjugate that combines a cereblon ligand based on Thalidomide and a linker commonly employed in PROTAC technology. This synthesized E3 ligase ligand-linker conjugate serves to facilitate targeted protein degradation.
Pack Size | Availability | Price/USD | Quantity |
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25 mg | 35 days | $ 494.00 |
Description | Thalidomide-O-C3-acid is a chemically derived conjugate that combines a cereblon ligand based on Thalidomide and a linker commonly employed in PROTAC technology. This synthesized E3 ligase ligand-linker conjugate serves to facilitate targeted protein degradation. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Synonyms | Thalidomide-O-C3-acid |
Molecular Weight | 360.322 |
Formula | C17H16N2O7 |
CAS No. | 2169266-64-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Thalidomide-O-C3-acid 2169266-64-0 ThalidomideOC3acid Thalidomide O C3 acid Thalidomide-O-C-3-acid inhibitor inhibit