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HOE 32020

Name: HOE 32020
Brand: TargetMol
SKU: T15495
Price: 135 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T15495 Copy Product Info

Purity: 98.40%

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HOE 32020 is a fluorescent dye and high-affinity DNA minor groove binder, specifically targeting A-T rich regions. It exhibits strong blue fluorescence upon DNA binding (Ex/Em: 352/461 nm) for nuclear imaging and cell cycle analysis.

HOE 32020

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Catalog No. T15495

Cas No. 23554-99-6

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Pack Size	Price	USA Stock	Global Stock
1 mg	$135	-	In Stock
5 mg	$347	-	In Stock
10 mg	$496	-	In Stock
25 mg	$873	-	In Stock
50 mg	$1,180	-	In Stock
1 mL x 10 mM (in DMSO)	$379	-	In Stock

In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:98.40%

Appearance:Solid

Color:Yellow

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	HOE 32020 is a fluorescent dye and high-affinity DNA minor groove binder, specifically targeting A-T rich regions. It exhibits strong blue fluorescence upon DNA binding (Ex/Em: 352/461 nm) for nuclear imaging and cell cycle analysis.
In vitro	HOE 32020 possesses potent DNA-binding capacity and is used for nuclear staining [1]. HOE 32020's fluorescence increases with pH, and it shows potential mutagenicity [2][3].

Chemical Properties

Molecular Weight	442.94
Formula	C₂₅H₂₃ClN₆
Cas No.	23554-99-6
Smiles	ClC=1C=CC(=CC1)C2=NC=3C=CC(=CC3N2)C4=NC5=CC=C(C=C5N4)N6CCN(C)CC6
Relative Density.	1.356 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 56 mg/mL (126.43 mM), Sonication is recommmended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2576 mL	11.2882 mL	22.5764 mL	112.8821 mL
5 mM	0.4515 mL	2.2576 mL	4.5153 mL	22.5764 mL
10 mM	0.2258 mL	1.1288 mL	2.2576 mL	11.2882 mL
20 mM	0.1129 mL	0.5644 mL	1.1288 mL	5.6441 mL
50 mM	0.0452 mL	0.2258 mL	0.4515 mL	2.2576 mL
100 mM	0.0226 mL	0.1129 mL	0.2258 mL	1.1288 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc