Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin , which is the inactive form of (-)-blebbistatin . Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereochemistry as the inactive (+)-blebbistatin enantiomer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 293.00 | |
5 mg | 35 days | $ 1,150.00 | |
10 mg | 35 days | $ 1,810.00 |
Description | (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin , which is the inactive form of (-)-blebbistatin . Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereochemistry as the inactive (+)-blebbistatin enantiomer. |
Molecular Weight | 323.3 |
Formula | C17H13N3O4 |
CAS No. | 1217619-62-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL
DMF: 20 mg/mL
DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
You can also refer to dose conversion for different animals. More
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(R)-nitro-Blebbistatin 1217619-62-9 (R) nitro Blebbistatin (R)nitroBlebbistatin nitro-Blebbistatin inhibitor inhibit