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Diamthazole hydrochloride (Synonyms: Dimazole hydrochloride)

Name: Diamthazole hydrochloride
Brand: TargetMol
SKU: T72212
Price: 100 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T72212 Copy Product Info

Purity: 99.63%

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Diamthazole hydrochloride is an effective broad-spectrum antifungal agent. It exerts bactericidal effects by specifically disrupting fungal metabolic homeostasis and inhibiting cell wall biosynthesis, showing significant in vitro activity against various dermatophytes causing tinea pedis and corporis.

Diamthazole hydrochloride

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🥰Excellent

Catalog No. T72212

Synonyms Dimazole hydrochloride

Cas No. 17140-69-1

Pack Size	Price	USA Stock	Global Stock
1 mg	$100	-	In Stock
5 mg	$247	-	In Stock
10 mg	$372	-	In Stock
25 mg	$787	-	In Stock
50 mg	$1,280	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.63%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Diamthazole hydrochloride is an effective broad-spectrum antifungal agent. It exerts bactericidal effects by specifically disrupting fungal metabolic homeostasis and inhibiting cell wall biosynthesis, showing significant in vitro activity against various dermatophytes causing tinea pedis and corporis.
In vitro	Diamthazole hydrochloride effectively suppresses the growth of cutaneous pathogens such as Trichophyton rubrum [1].
Synonyms	Dimazole hydrochloride

Chemical Properties

Molecular Weight	329.89
Formula	C₁₅H₂₄ClN₃OS
Cas No.	17140-69-1
Smiles	Cl.N=1C=2C=CC(OCCN(CC)CC)=CC2SC1N(C)C

Storage & Solubility Information

Storage

Keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (242.51 mM), Sonication is recommmended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0313 mL	15.1566 mL	30.3131 mL	151.5657 mL
5 mM	0.6063 mL	3.0313 mL	6.0626 mL	30.3131 mL
10 mM	0.3031 mL	1.5157 mL	3.0313 mL	15.1566 mL
20 mM	0.1516 mL	0.7578 mL	1.5157 mL	7.5783 mL
50 mM	0.0606 mL	0.3031 mL	0.6063 mL	3.0313 mL
100 mM	0.0303 mL	0.1516 mL	0.3031 mL	1.5157 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc