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Curculigoside B is a naturally occurring phenolic compound traditionally used in Asian to protect against osteoporosis and maintaining skeletal integrity. Curculigoside B exerts antioxidant, anti-aging, immunomodulatory, and anti-inflammatory functions, while effectively preventing pathological bone loss, establishing this compound as a validated osteoprotective therapeutic candidate of increasing interest in research.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $48 | - | In Stock | |
| 5 mg | $123 | - | In Stock | |
| 10 mg | $179 | - | In Stock | |
| 25 mg | $297 | - | In Stock | |
| 50 mg | $453 | - | In Stock | |
| 100 mg | $653 | - | In Stock |
| Description | Curculigoside B is a naturally occurring phenolic compound traditionally used in Asian to protect against osteoporosis and maintaining skeletal integrity. Curculigoside B exerts antioxidant, anti-aging, immunomodulatory, and anti-inflammatory functions, while effectively preventing pathological bone loss, establishing this compound as a validated osteoprotective therapeutic candidate of increasing interest in research. |
| In vitro | Six phenolic compounds were isolated from Curculigo orchids, including 2,6-dimethoxy benzoic acid (1), Curculigoside A (2), Curculigoside B (3), Curculigoside A (4), Cucurigigine D (5), and 3,3',5,5'-tetramethoxy-7,9':7',9-diepoxylignan-4,4'-di-O-beta-D-glucopyranoside (6). All six compounds promoted osteoblast proliferation, while compounds (1), (2), and (4) also slightly enhanced osteoblast ALP activity. Compounds (1), (2), (3), (6), and the ethanol extract reduced bone resorption pit area, osteoclast formation, and TRAP activity [1]. |
| Molecular Weight | 452.41 |
| Formula | C21H24O11 |
| Cas No. | 143601-09-6 |
| Smiles | C(OCC1=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=CC(O)=C1)(=O)C3=C(OC)C=CC=C3O |
| Relative Density. | 1.31g/cm3 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: ≥ 40 mg/mL, Sonication is recommeded. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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