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Nattokinase
🥰Excellent
Catalog No. T38736Cas No. 133876-92-3
Alias Nattokinase (Natto fermentation)
Nattokinase is a serine protease derived from nattō, exhibiting oral bioavailability and fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1 to dissolve thrombi while inhibiting platelet aggregation, making it suitable for cardiovascular disease and Alzheimer's disease research.
Nattokinase
🥰Excellent
Catalog No. T38736Alias Nattokinase (Natto fermentation)Cas No. 133876-92-3
Nattokinase is a serine protease derived from nattō, exhibiting oral bioavailability and fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1 to dissolve thrombi while inhibiting platelet aggregation, making it suitable for cardiovascular disease and Alzheimer's disease research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $32 | - | In Stock | |
| 5 mg | $73 | - | In Stock | |
| 10 mg | $123 | - | In Stock | |
| 25 mg | $215 | - | In Stock | |
| 50 mg | $328 | - | In Stock | |
| 100 mg | $562 | - | In Stock | |
| 200 mg | $783 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Nattokinase is a serine protease derived from nattō, exhibiting oral bioavailability and fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1 to dissolve thrombi while inhibiting platelet aggregation, making it suitable for cardiovascular disease and Alzheimer's disease research. |
| In vitro | After 8 hours of treatment with Nattokinase (62.5-2000 FU), the lysis rate of MSLN CAR-T cells against HCC1806 cells significantly increased at all tested E/T ratios. Similarly, when treated with Nattokinase (125-2000 FU), the lysis rate of MSLN CAR-T cells against OVCAR3 cells also showed a significant increasing trend under different E/T ratio conditions [4]. |
| In vivo | Methods: Nattokinase (150, 250 mg/kg; twice daily; for 2 days) was administered orally to rat thrombosis models to investigate the antithrombotic effects of Nattokinase in vivo. Results: The plasma FDPs and D-dimer levels in both the low-dose Nattokinase group and the high-dose Nattokinase group were significantly higher than those in the negative control group. No significant difference was observed in FDPs and D-dimer levels between the high-dose Nattokinase group and the Vermis kinase positive control group. Parazacco spilurus subsp. spilurus.[3] |
| Synonyms | Nattokinase (Natto fermentation) |
| Cas No. | 133876-92-3 |
| Relative Density. | no data available |
| Color | Yellow |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: 80 mg/mL, Sonication is recommended. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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